RCT Clinical Trial
Improving Quality of Life for People Living with Dementia
Rachel Convery, Ken Mills, Sarah M McGhee, Bruce Elliott, Helen McAskill, Anne Mills
Presented at the Hospice UK Annual Conference, November 2021
Dementia presents a major challenge for health care systems with aging populations. Over 46 million people live with dementiaworldwide. This is estimated to increase to 131.5 million by 2050. (1)
Much of the care for the person with dementia (PWD), in the early stages, takes place at home, therefore, there is a growing need for an evidence-based approach to home support for PWD and their carers. (2)
Aim: This study will assess the impact of a new, personalised memory games application (App), on the quality of life (QoL) of PWD and their carer(s)
Single site, randomised controlled study.
30 pairs: PWD and informal carer randomised to two groups with 2:1 intervention to control allocation ratio.
Quality of life of PWD and their carers: DEMQOL (5) /C-DEMQOL (6) scores compared to comparator group.
Unanticipated effects of using the personalised App, compared to the non-personalised App.
Feasibility and acceptability of study instruments (i.e. areas of quality of life, communication, and cognitive function): specific questions, interview findings and adherence
Qualitative Data Analysis:
Thematic and narrative analysis of interview transcripts.
Feasibility and acceptability assessed at week 13 and at the conclusion.
Quantitative Data Analysis:
Primary Analyses: DEMQOL and C-DEMQOL
Secondary Analysis: Content of, and adherence to, the intervention to explore the effect on the scores.
Engagement with the personalised content may lead to improvement in the QoL of the PWD and/or their carer by facilitating and improving communication
View the full study here:
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trends. [Homepage]. United Kingdom: Alzheimer’s Disease International; 2015 [updated 1 October 2015; 6th March 2017]. Available from: https://www.alz.co.uk/research/WorldAlzheimerReport2015.pdf
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randomised controlled trial. Trials 19, 546 (2018). https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-2933-8#Sec2
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quality of life for people with dementia: DEMQOL. Psychological Medicine, 37, 737-746.
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dementia: development and validation of C-DEMQOL. Quality of Life Research. Vol. 29, 2019, pp. 2299-2310.